C Synergy (formerly Collagen C)

C Synergy™, is a supplement to support collagen production and contains antioxidant vitamin C to support healthy connective tissue.*

• Supports and promotes normal immune system response function*
• Provides whole food acerola and rose hips
• Excellent source of antioxidant vitamin C, which is involved in the production of collagen

What Collagen Does

Collagen is a protein molecule made up of amino acids. It provides structural support between cells that make up the inner layers of connective tissues in our skin¹. The connective tissue in the inner (middle) layer of the skin is composed of collagen and elastin fibers, which maintain the tension and elasticity of skin.^2,3

Vitamin C and Skin Health

The antioxidant properties of vitamin C and its role in collagen synthesis make it a vital molecule for skin health. Vitamin C’s antioxidant activity is particularly important in the top (epidermal) layer of our skin,⁴ where its concentration is 425% higher than in the dermis.² Ultraviolet light, especially UVA, is a common factor that induces skin oxidative stress.^2,5 The antioxidant activity of vitamin C helps protect against UV-induced damage caused by free radicals.⁶

Cell culture studies have shown that addition of vitamin C might influence the ability of the skin to protect itself from water loss.^4,7,8

Cited References:

1. Block G, Jensen CD, Morrow JD, Holland N, Norkus EP, Milne GL, et al. Free radical biology & medicine. 2008;45(4):377-84. Epub 2008/05/06. doi: 10.1016/j.freeradbiomed.
2. Wang K, Jiang H, Li W, Qiang M, Dong T, Li H. Frontiers in Physiology. 2018;9. doi: 10.3389/fphys.2018.00819.
3. Hadjighassem M, Kamalidehghan B, Shekarriz N, Baseerat A, Molavi N, Mehrpour M, et al. Nutrition journal. 2015;14:20. Epub 2015/04/19. doi: 10.1186/s12937-015-0012-5.
4. Pullar JM, Carr AC, Vissers MCM. Nutrients. 2017;9(8):866. doi: 10.3390/nu9080866.
5. McArdle F, Rhodes LE, Parslew R, Jack CI, Friedmann PS, Jackson MJ. Free radical biology & medicine. 2002;33(10):1355-62. Epub 2002/11/07. doi: 10.1016/s0891-5849(02)01042-0.
6. De Filippo C, Cavalieri D, Di Paola M, Ramazzotti M, Poullet JB, Massart S, et al. Proceedings of the National Academy of Sciences of the United States of America. 2010;107(33):14691-6. Epub 2010/08/04. doi: 10.1073/pnas.1005963107.
7. Savini I, Catani MV, Rossi A, Duranti G, Melino G, Avigliano L. The Journal of investigative dermatology. 2002;118(2):372-9. Epub 2002/02/14. doi: 10.1046/j.0022-202x.2001.01624.x.
8. Boyce ST, Supp AP, Swope VB, Warden GD. The Journal of investigative dermatology. 2002;118(4):565-72. Epub 2002/03/29. doi: 10.1046/j.1523-1747.2002.01717.x.

* These statement have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.