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Supplies 5 mg of biologically active folate called (6S) 5-methyltetrahydrofolate (5-MTHF).

Folate is a vitamin that humans cannot synthesize or store well because of its water soluble nature. Folates are normally found in a wide variety of foods and are commonly consumed through a diet of green leafy vegetables, sprouts, fruits, and animal products such as milk and dairy products, egg yolk and liver, however, storage and heat during cooking may decrease the bioavailability by almost 95%. Folic acid and food containing folate are not biologically active in the human body. To convert these forms to the biologically active 5-methyltetrahydrofolate (5-MTHF) requires a key enzyme, methylenetetrahydrofolate reductase (MTHFR), which is considered one of the most important enzymes in human physiology. There is a large percentage of the population with a genetic mutation that limits the conversion of folate to its reduced active form, MTHF.

The general healthy adult population daily recommendation for folate intake is 400 mcg of folic acid, however a greater amount may be required if MTHFR enzyme is not present. Women planning pregnancy or who are pregnant require higher intakes of folate to support neural tube development. Quatrefolic® is a highly soluble glucosamine salt of 5-MTHF which has been shown to have more rapid absorption than folic acid.

  • Cardiovascular Health Support
  • Mood Support

Methyl Folate is a useful dietary supplement for those individuals that prefer a high dose active form of folic acid called (6S) 5-MTHF.

Suggested Usage

Adults take 1 tablet daily or as directed by a healthcare professional.


  • Serving Size: 1 Vegetarian Tablet
  • Servings Per Contaier: 60
  • Amount Per Serving:
  • Folate 8,333 mcg DFE mg 2,083%
  • -(As Quatrafolic®(6S)-5-MTHF acid, glucasamine salt))(5,000 mcg L-5-MTHF)

Other ingredients: Microcrystalline cellulose and hydroxypropyl methylcellulose (capsule)

This product contains NO yeast, wheat, gluten, soy, milk/dairy, sodium, sugar, starch, artificial preservatives, artificial flavoring, or genetically modified organisms (GMOs).


Doses of 5 mg or higher per day can cause abdominal cramps, diarrhea, and rash.

If you are pregnant, nursing, taking any medication or have a medical condition, please consult your healthcare practitioner before taking any dietary supplement.

Use only if safety seal is intact.

Keep out of reach of children.

Additional Information

Store in a cool, dry place, away from direct light.

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