SAMe 200 Mg

Jarrow Formulas® SAMe 200 provides a full 200 mg SAMe (net yield) from 400 mg of SAMe tosylate disulfate. SAMe 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.

Found in all living cells, SAMe is a metabolite of methionine (an essential amino acid). SAMe is a chiral molecule consisting of two form (S,S) SAMe and (R,S) SAMe. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas® SAMe is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S) SAMe the highest active level available.

SAMe supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue known as glycoaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAMe metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate.

SAMe methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine, and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).

SAMe metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase, glutathione reductase and glutathione-S-transferase), which are components of the body's endogenous antioxidant network and important for liver function, including phase II detoxification.