Mega SporeBiotic

16 Reviews

Capsules 180

Mega SporeBiotic by Microbiome Labs is a spore-based probiotic blend that supports a healthy gut environment, promotes microbial diversity, and maintains gut barrier function.
See product ingredients
SKU: mega-sporebiotic-MCBL
$63.99 to $165.99
In Stock
Ships today if you order in the next 1 hours 40 minutes.
$63.99 to $165.99
In Stock
Ships today if you order in the next 1 hours 40 minutes.

Product Details

Product Code: mega-sporebiotic-MCBL-180-cpsls

Quantity per Container: 180 Capsules

Microbiome Labs Mega SporeBiotic

Microbiome Labs Mega SporeBiotic is a spore-based, broad-spectrum probiotic supplement clinically shown to help maintain a healthy gut barrier and immune function. It has a 5-year shelf-life, does not require refrigeration, and maintains efficacy even while taking antibiotics.

How Mega SporeBiotic Works

Mega SporeBiotic features a unique all-spore formula of 5 Bacillus spores that remain dormant until they reach the large intestine in the gastrointestinal tract. This proprietary probiotic blend of spore strains includes Bacillus indicus, Bacillus subtilis, Bacillus coagulans, Bacillus licheniformis, and Bacillus clausii.

Unlike Lactobacillus-type probiotics, Bacillus probiotics are dormant spore forms until they reach your gastrointestinal tract and can start to colonize. This makes them shelf stable. Once in the gut, the Bacillus spores transform into an active spore form and start colonizing within the gut and gastric system, delivering their benefits to your body. (1)

The unique spore probiotic formula reconditions and helps repair the gut by promoting a diverse microbiome and promoting “good” bacteria in the gut and digestive system. Bacillus probiotic strains, which are considered beneficial microbes, also have more tolerance under hostile environments, making them ideal for dietary supplements. (2)

Why Choose Mega SporeBiotic?

Unlike its Lactobacillus counterparts, this 5-Bacillus spore probiotic blend is more shelf stable and offers dual gut health and immune system support, as well as other potential health benefits.

Mega SporeBiotic Benefits

  • Shelf stable, spore probiotic blend
  • Professional-grade formula
  • Supports healthy GI tract
  • Provides antioxidants for immune system support
  • This formula meets or exceeds cGMP quality standards
  • No refrigeration required

Probiotics help support gut health and overall wellness by promoting a healthy gut microbiome. The gut is where the immune system starts, so maintaining a healthy gut also promotes healthy immune function. (3) A healthy microbiome features balanced levels of microorganisms (about 300 to 500 different species of bacteria) living naturally in your intestines and digestive system, which help your body's internal immune response, weight management, and normal digestion.

The Food and Drug Administration (FDA) recommends consulting with your healthcare practitioner before giving supplements to children under 5 years old.

Mega SporeBiotic from Microbiome Labs provides shelf-stable support for gut health and healthy immune function. The formula has been carefully vetted and approved for quality by our certified natural healthcare practitioners.

Try this trusted probiotic supplement with food. Shop for Microbiome Labs Mega SporeBiotic from NHC, and experience the difference its 5 probiotic strains make to your health and wellness for yourself.

Ratings & Reviews

16 reviews

  • 3 stars
  • 0 reviews
  • 2 stars
  • 0 reviews
  • 1 star
  • 0 reviews
8/26/2019 12:00:00 am

I buy again & again!

by Peggy -

Great customer service and always free shipping!

Not medical or professional advice

10/8/2019 12:00:00 am

Good product will keep buying.

by julie -

I use this as it was suggested by my naturopathic Dr.

Not medical or professional advice

5/2/2020 12:00:00 am

Great product

by Frank -

Keeping me healthy for over a year now. I'm very pleased !

Not medical or professional advice

7/8/2020 12:00:00 am

will look for less expensive one

by Nelda -

superior product but too expensive

Not medical or professional advice

7/9/2020 12:00:00 am


by Jennifer -

Follow directions to slowly begin to give your body a chance to adapt, but the wonderful thing is this: when you reach the full-dose of 2 capsules per day, it COMPLETELY REPOPULATES YOUR GUT IN 3 WEEKS!! What a difference for both me and my husband! And once you're done with the 3 weeks at full dose, you can choose to do maintenance dose if you'd like. We use 2 caps every 3rd day for maintenance. Great product!!! Thanks MegaSpore!

Not medical or professional advice

7/10/2020 12:00:00 am


by Renee -

It appears to be helping. I progress to 1 tablet slowly.

Not medical or professional advice

9/7/2020 12:00:00 am

Great probiotic!

by Grace -

It was recommended by my doctor several years ago, and I've been taking it ever since. Gut health and brain health go hand in hand, I was told.

Not medical or professional advice

12/12/2020 11:00:00 pm

Log in trouble

by theresa -

Products great Just having trouble with trying to reorder on site

Not medical or professional advice

1/5/2023 1:34:00 pm

Great Probiotic

by Stacy

Great probiotic for IBS and other digestive issues.

Not medical or professional advice

5/5/2023 12:43:00 pm


by Pamela

This is my personal favorite and have been using for many years with faith to be the best

Not medical or professional advice

6/26/2023 4:21:00 pm

Mega SporeBiotic

by Kat

Best probiotics out there! I never get bloating or stomach issues anymore and my immune system has been great!

Not medical or professional advice

7/6/2023 12:49:00 pm


by T

recommended product but you need to take it regularly

Not medical or professional advice

9/10/2023 4:27:00 pm

Great probiotic

by Grace

my functional medicine doctor recommended this to rebuild my gut microbiome. it cleared my hormonal acne!

Not medical or professional advice

9/14/2023 5:56:00 pm

Great Product - Mega SporeBiotic

by Lynn

It was recommended at one of my quarterly appointments with the ARNP to start taking a quality probiotic. She suggested Mega SporeBiotic. I have been taking this probiotic for several years and certain skin issues (palms of both hands) have been cleared up. Before Mega SporeBiotic, I was miserable. Now my skin (hands) is clear and I am a happy woman.

Not medical or professional advice

10/22/2023 7:09 pm

Noticeable results

by DB

I am in my 40s and over the past couple of years have dealt with dental issues for which I had to use antibiotics. Since then, I have been trying all different brands of probiotics. Most had no noticeable effect. But, with this one, I am impressed. It is certainly doing something to clear my body after taking it just a few days! I will continue to use this supplement and hope it replenishes my good bacteria.

Not medical or professional advice

11/25/2023 12:57 pm

Doctor recommended this brand

by Betty

This is the probiotic recommended by my integrative physician more than 5 years ago, and I've been taking it ever since.

Not medical or professional advice