Nerve and Mitochondrial Health
Brand: Pure Encapsulations
Product Code: adenosyl-hydroxy-b12-PEC
Servings per Container: 90
Quantity per Container: 90 Capsules
Adenosyl/Hydroxy B12 offers a unique blend of vitamin B12 to promote nerve and mitochondrial health. Hydroxycobalamin is a precursor form of vitamin B12 converted in the body to both methylcobalamin and adenosylcobalamin.
While methylcobalamin is found in the cytosol of cells and predominates in blood and other fluids, adenosylcobalamin is the major form of vitamin B12 stored in the mitochondria of cellular tissues. It is a key cofactor in carbohydrate metabolism for the enzyme methylmalonyl-CoA mutase used to produce succinyl-CoA. Optimal levels also support healthy synthesis of neuronal myelin.
Take 1 capsule, 1–3 times daily, with meals.
- Serving Size: 1 capsule
- Amount per serving:
- Vitamin B12 2,000 mcg
- -(as adenosylcobalamin and 50% hydroxycobalamin)
Other Ingredients: hypoallergenic plant fiber (cellulose), vegetarian capsule (cellulose, water).
Non-GMO. Certified gluten free.
If you are pregnant or lactating, have any health condition, or are taking any medication, consult your health professional before use.
Keep out of reach of children.
Use only if safety seal is intact.
Store sealed in a cool, dry place.
Ratings & Reviews
Really helped my symptoms
by kristin -
I have the MTHFR mutation that limits utilization of B12 that has be absorbed from cyanocobalamin supplements. For over a year I had several symptoms of reduced utilization of B12, including painful inflammation of my mouth tissues. Once starting these (and another natural-form B12 supplement), my symptoms went away after a month.
would buy again
by Marti -
I stay more alert taking this
by Patricia -
Good combo of B12 without the cyan cobalamin.
Great for MTHFR gene mutation patients
by AshleySB -
Great for those who have an MTHFR gene mutation. I have seen great improvements from switching to this adenosyl/hydroxy blend last year, even from using a methylated version before.
by Billye -
I have the MTHFR gene. This B12 is perfect for me.
by Bob -
Great B12 Supplement
by Ty -
This is an excellent Vitamin B12 supplement. Adenosylcobalamin is critically important and required for the methylation process. Adenosylcobalamin is also critically important for the health of the liver, brain, and nervous system. I like that this product comes in a small vegan capsule. It is also free of chemical additives such as magnesium stearate, citric acid, and ""natural flavors"" produced from monosodium glutamate that are found in most Vitamin B12 supplements.
Great if you react to other B12's
by Ela -
This is high quality B12. My genetic testing indicates that this combination is best for me. It is the only hydroxy and adenosyl I have found that is free of ingredients I cannot tolerate. Simply the best.