SAM-e Plus

by Karuna
4 Reviews

Tablets 60

Enteric-coated tablets with methylation and transulfuration co-factors

SKU: sam-e-plus-KRU-60-tblts

Product Details

Product Code: sam-e-plus-KRU-60-tblts

Servings per Container: 60 Tablets

Over a decade of rigorous clinical studies in Europe and elsewhere have established SAM-e (S-adenosyl-L-methionine, an essential methylation and transulfuration cofactor) as a useful tool for supporting normal mood regulation, and joint and liver health. SAM-e increases cell membrane fluidity, up-regulates neurotransmitter receptor number, and enhances neurotransmitter receptor affinity. SAM-e supports healthy joints both by increasing the number of articular chondrocytes, and by stimulating the synthesis of protective sulfated proteoglycans therein. SAM-e also protects synovial cells against pro-inflammatory prostanoids, and blocks enzymes that degrade cartilage. SAM-e is a precursor of the critical antioxidant glutathione, a key molecule in the detoxification process in the liver. SAM-e Plus contains the tosylate form of SAM-e as used extensively in clinical trials, and includes several other ingredients found in studies to support and facilitate these functions. SAM-e Plus tablets are enterically-coated, essential for preventing demethylation in the stomach.

Professional Brand

Scientifically formulated, pharmaceutical grade supplements meet or exceed the highest standards of excellence from formulation through raw materials testing and current good manufacturing processes (cGMP). Third party independent testing assures superior quality, enhanced absorption, purity, potency, efficacy and truth in labeling.

Ratings & Reviews

4 reviews

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4/21/2015 12:00:00 am


by Antran -

Easy to take and recommended by my Doctor - I notice an improvement in mood and attitude with work, family life in general! The Dr suggested take 2 in the morning & 2 in the evening - I thought that might be excessive - but for me 4 did the trick after tr

2/14/2015 11:00:00 pm


by Antran -

I've tried other Sam-e products for years...but the Karuna SAM-e Plus is THE BEST!!! My Holistic Doctor...who's also our family doctor...recommended this brand about a year ago - 2 in the morning, 2 in the evening - which I thought was a lot - but it's th

9/1/2014 12:00:00 am


by Healthy62 -

My holistic doctor recommended this particular brand and dose for my teen. I used to take a different brand...but decided I'd try this one myself. About two weeks later my teen lost much of her ""angst"" and I found my mood and energy level to be much im

7/21/2014 12:00:00 am

good product

by cb -

I like this product because it has the B vitamins included so you don't have to take another pill with your sam-e. make sure you take it with food to avoid stomach upset.