{"product_id":"bio-flex-iii-by-biospec","title":"Bio-Flex III, by BioSpec","description":"\u003ch4\u003e\r\n  Bio-Flex III Broad Spectrum Formula\r\n\u003c\/h4\u003e\r\n\u003cp\u003e\r\n  \u003cbr\u003e\r\n  Bio-Flex III is a comprehensive joint-support formula designed to promote comfort, flexibility, and healthy mobility with a targeted blend of glucosamine sulfate, chondroitin sulfate, curcumin, Boswellia, vitamin C, manganese, and BioPerine®.* It was developed to emphasize ingredients and standardizations with the strongest human clinical rationale for supporting joint function, especially in adults experiencing age-related joint stiffness, occasional discomfort, or reduced ease of movement. Its updated design focuses on more clinically meaningful amounts of key ingredients and a more targeted botanical strategy than the previous Bio-Flex II formula.\r\n\u003c\/p\u003e\r\n\u003cp\u003e\r\n  \u003cbr\u003e\r\n  \u003cstrong\u003eIngredient Highlights\u003c\/strong\u003e\r\n\u003c\/p\u003e\r\n\u003cp\u003e\r\n  \u003cbr\u003e\r\n  \u003cstrong\u003eGlucosamine Sulfate (2000 mg)\u003c\/strong\u003e\r\n\u003c\/p\u003e\r\n\u003cp\u003e\r\n  Glucosamine sulfate is included to support cartilage structure and long-term joint integrity. In a 2024 systematic review and meta-analysis of randomized trials, glucosamine sulfate showed a significant benefit for reducing tibiofemoral joint-space narrowing, supporting its role in preserving joint structure over time.*\r\n\u003c\/p\u003e\r\n\u003cp\u003e\r\n  \u003cbr\u003e\r\n  \u003cstrong\u003eChondroitin Sulfate (1000 mg)\u003c\/strong\u003e\r\n\u003c\/p\u003e\r\n\u003cp\u003e\r\n  Chondroitin sulfate is one of the most clinically relevant ingredients in the formula for joint comfort and physical function. Human trials and meta-analytic data show that chondroitin sulfate can help reduce pain, improve physical function, and support the resilience and hydration of cartilage. In a large controlled trial, 800 mg\/day pharmaceutical-grade chondroitin sulfate was superior to placebo and similar to celecoxib for improving pain and function over 6 months in symptomatic knee osteoarthritis.*\r\n\u003c\/p\u003e\r\n\u003cp\u003e\r\n  \u003cbr\u003e\r\n  \u003cstrong\u003eCurcumin Extract (95% Curcuminoids) (1000 mg)\u003c\/strong\u003e\r\n\u003c\/p\u003e\r\n\u003cp\u003e\r\n  Curcumin is a leading botanical ingredient for joint comfort, stiffness, and mobility. A 2024 Bayesian network meta-analysis of 23 randomized controlled trials involving 2,175 patients found that curcumin significantly improved pain and WOMAC scores versus placebo, and a multicenter human trial in 367 patients found Curcuma domestica extract comparable to ibuprofen for pain and function with fewer gastrointestinal complaints.*\r\n\u003c\/p\u003e\r\n\u003cp\u003e\r\n  \u003cbr\u003e\r\n  \u003cstrong\u003eBoswellia serrata Extract (30% AKBA) (100 mg)\u003c\/strong\u003e\r\n\u003c\/p\u003e\r\n\u003cp\u003e\r\n  Boswellia in Bio-Flex III is standardized to 30% AKBA, the boswellic-acid fraction most directly linked to human osteoarthritis research. In a double-blind, randomized, placebo-controlled trial, a 30% AKBA Boswellia extract (5-Loxin®) significantly improved pain and physical function in adults with knee osteoarthritis and also reduced MMP-3, an enzyme associated with cartilage breakdown.*\r\n\u003c\/p\u003e\r\n\u003cp\u003e\r\n  \u003cbr\u003e\r\n  \u003cstrong\u003eVitamin C (Ascorbate Complex) (260 mg)\u003c\/strong\u003e\r\n\u003c\/p\u003e\r\n\u003cp\u003e\r\n  Vitamin C provides foundational support for joint tissues because it is required for collagen biosynthesis and functions as an important physiological antioxidant. Since collagen is a major structural component of connective tissue, vitamin C helps support the integrity of cartilage, ligaments, tendons, and other joint-supporting tissues.*\r\n\u003c\/p\u003e\r\n\u003cp\u003e\r\n  \u003cbr\u003e\r\n  \u003cstrong\u003eManganese (as manganese glycinate) (2 mg)\u003c\/strong\u003e\r\n\u003c\/p\u003e\r\n\u003cp\u003e\r\n  Manganese is a trace mineral that contributes to bone formation, antioxidant defense, and connective tissue support. The NIH Office of Dietary Supplements notes that manganese is a cofactor for enzymes involved in bone formation and reactive oxygen species scavenging, making it a supportive nutrient for healthy musculoskeletal aging.*\r\n\u003c\/p\u003e\r\n\u003cp\u003e\r\n  \u003cbr\u003e\r\n  \u003cstrong\u003eBioPerine® (Piperine) (4 mg)\u003c\/strong\u003e\r\n\u003c\/p\u003e\r\n\u003cp\u003e\r\n  BioPerine® is included to support the bioavailability of curcumin. Piperine has been shown in human pharmacokinetic research to increase curcumin exposure, which is why Bio-Flex III pairs a meaningful curcumin dose with a recognized absorption-support ingredient.*\r\n\u003c\/p\u003e\r\n\u003cp\u003e\r\n  \u003cbr\u003e\r\n  *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\r\n\u003c\/p\u003e\u003ch2\u003eSuggested Usage\u003c\/h2\u003e\u003cp class=\"productDetailTextSection\"\u003eAs a nutritional supplement for adults, take 2-4 tablets daily or as directed by your Healthcare Professional. \u003c\/p\u003e\u003ch2\u003eIngredients\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eServing Size:\u003c\/strong\u003e 4 Tablets\u003cbr\u003e\u003cstrong\u003eServings Per Container:\u003c\/strong\u003e 30\u003cbr\u003e\u003cstrong\u003eAmount Per Serving \/ %DV:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eVitamin C (ascorbate complex) 260 mg \/ 289%\u003c\/li\u003e\n\u003cli\u003eManganese (as manganese glycinate) 2 mg \/ 87%\u003c\/li\u003e\n\u003cli\u003eGlucosamine Sulfate (as glucosamine sulfate potassium chloride complex) 2,000 mg \/ †\u003c\/li\u003e\n\u003cli\u003eChondroitin Sulfate 1,000 mg \/ †\u003c\/li\u003e\n\u003cli\u003eCurcumin Extract (standardized to 95% curcuminoids) 1,000 mg \/ †\u003c\/li\u003e\n\u003cli\u003eBoswellia serrata Extract (standardized to 30% AKBA) 100 mg \/ †\u003c\/li\u003e\n\u003cli\u003eBioPerine® (\u003ci\u003ePiper nigrum\u003c\/i\u003e) (standardized to min 95% piperine) 4 mg \/ †\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e†% Daily Value not established.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eOther Ingredients:\u003c\/strong\u003e Dicalcium Phosphate Dihydrate, Stearic Acid, Microcrystalline Cellulose, Croscarmellose Sodium, Magnesium Stearate, Silicon Dioxide, and Pharmaceutical Glaze.\u003c\/p\u003e\u003ch2\u003eWarnings\u003c\/h2\u003e\u003cp class=\"productDetailTextSection\"\u003e\u003cstrong\u003eDo not use if allergic to shellfish.\u003c\/strong\u003e\u003c\/p\u003e\u003cp class=\"productDetailTextSection\"\u003eIf you are pregnant, nursing, taking any medication, or have a medical condition, please consult your healthcare practitioner before taking any dietary supplement.\u003c\/p\u003e\u003cp class=\"productDetailTextSection\"\u003eKeep out of reach of children.\u003c\/p\u003e","brand":"BioSpec","offers":[{"title":"120 Tablets","offer_id":52420196630895,"sku":"bio-flex-iii-BSP-120-tblts","price":55.99,"currency_code":"USD","in_stock":true},{"title":"240 Tablets","offer_id":52420196663663,"sku":"bio-flex-iii-BSP-240-tblts","price":92.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0917\/0940\/7599\/files\/bio-flex-iii-BSP_120_20Tablets_main_1_3c3d419d-0f10-4b7a-87ab-7282e54bb939.jpg?v=1780432439","url":"https:\/\/www.professionalsupplementcenter.com\/products\/bio-flex-iii-by-biospec","provider":"Professional Supplement Center","version":"1.0","type":"link"}