B-Complex #12 by Thorne Research

9 Reviews

Capsules 60

B-vitamin complex with extra B12 and folate

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SKU: b-complex-12-THR
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Product Details

Brand: Thorne Research

Product Code: b-complex-12-THR

Servings per Container: 60

Quantity per Container: 60 Capsules

B Complex #12 supports energy production and healthy neurological function. Unlike many multi-B vitamins, it contains the active forms of eight water-soluble B vitamins.

Supplementing with the active forms of the B vitamins is extremely important to everyone, especially individuals who might not be able to convert non-active B vitamins to their active forms in the liver because of compromised liver function, poorly functioning enzymes, digestive disorders, or increasing age. Vitamin B12 and folate are necessary for normal red blood cell formation, tissue and cellular repair, normal methylation and homocysteine metabolism, and DNA synthesis.

Thorne's B-Complex #12 supplies the two active forms of vitamin B12 – adenosylcobalamin and methylcobalamin – as well as the two active forms of folate – folinic acid and 5-MTHF. The other bioactive forms of the B vitamins in each capsule ensures you will get the most bioavailable vitamin B complex available. B-Complex #12 is not derived from yeast.

Most of the B vitamins, with the exception of vitamin B12, are not stored in the body; consequently, they must be acquired daily from the diet in order to maintain optimal health. Vitamin B12 deficiency can be manifest with varying degrees of mental changes, such as confusion and irritability. Certain prescription medications (for seizures, diabetes, arthritis, and cancer) can cause a deficiency of these important vitamins. The incidence of vitamin B12 and/or folate deficiency is high among the elderly. Pregnant women require an increased amount of folate for proper fetal development. A woman who has a folate deficiency prior to pregnancy can expect that deficiency to be intensified during pregnancy.

B Complex #12 includes eight water-soluble B vitamins: thiamin (vitamin B1); riboflavin/riboflavin 5'-phosphate (vitamin B2); niacinamide (vitamin B3); pantothenic acid (vitamin B5); pyridoxine/pyridoxal 5'-phosphate (vitamin B6); methyl- and adenosylcobalamin (vitamin B12); folinic acid and 5-MTHF (folate); and biotin; plus choline. Although each B vitamin is chemically distinct, they often work synergistically in various biochemical functions throughout the body – from cellular energy production, to healthy red blood cell formation, to healthy neurological function.

A nutritional supplement that contains these active cofactors has enhanced bioavailability, ensuring the body gets the nutrients it needs.

Ratings & Reviews

9 reviews

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8/31/2011 12:00:00 am

Big fan.

by Not so sleepy in NYC -

I used to suffer from fatigue in the early morning and late afternoon. I now take one capsule when I wake up (on an empty stomach) and feel energized throughout the day.

Not medical or professional advice

11/30/2011 11:00:00 pm

Great B Complex

by Healthy Mom to be -

Great B Complex formula with bioavailable form of folic acid. Using for prenatal support.

Not medical or professional advice

10/16/2012 12:00:00 am

Great product

by Suzy -

I was vitamin B deficient and had a tingling in my hands. Since taking this product the tingling has gone away and I have a lot more energy. Highly recommend this product.

Not medical or professional advice

12/11/2012 11:00:00 pm

Great product

by Suzy -

Easy to take and really helps me feel better.

Not medical or professional advice

7/29/2013 12:00:00 am

The Best

by Abbie -

I take one a day first thing in the morning (on an empty stomach) and it has made a huge difference on my energy levels. I used to feel lethargic in the morning and start dragging again by evening, but now I have consistent, natural-feeling energy throughout the day.

Not medical or professional advice

4/23/2017 12:00:00 am


by N

Love this and take it up to 3 times a day but at least once a day for substained energy and mood

Not medical or professional advice

1/6/2018 11:00:00 pm

Good Product

by None -


Not medical or professional advice

12/15/2020 11:00:00 pm

i would buy this product again


helps with methylation issues. take it always.

Not medical or professional advice

9/9/2023 10:58 am

Good product!

by Barbara -

I have taken this for years, and I can tell the difference if I don’t take it. Namely less energy, feeling tired. Will continue to use it.

Not medical or professional advice