Adenosyl/Hydroxy B12

by Pure Encapsulations
8 Reviews

Capsules 90

Nerve and Mitochondrial Health

SKU: adenosyl-hydroxy-b12-PEC

Product Details

Brand: Pure Encapsulations

Product Code: adenosyl-hydroxy-b12-PEC

Servings per Container: 90

Quantity per Container: 90 Capsules

Adenosyl/Hydroxy B12 offers a unique blend of vitamin B12 to promote nerve and mitochondrial health. Hydroxycobalamin is a precursor form of vitamin B12 converted in the body to both methylcobalamin and adenosylcobalamin.

While methylcobalamin is found in the cytosol of cells and predominates in blood and other fluids, adenosylcobalamin is the major form of vitamin B12 stored in the mitochondria of cellular tissues. It is a key cofactor in carbohydrate metabolism for the enzyme methylmalonyl-CoA mutase used to produce succinyl-CoA. Optimal levels also support healthy synthesis of neuronal myelin.

Ratings & Reviews

8 reviews

  • 3 stars
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3/19/2020 12:00:00 am

Really helped my symptoms

by kristin -

I have the MTHFR mutation that limits utilization of B12 that has be absorbed from cyanocobalamin supplements. For over a year I had several symptoms of reduced utilization of B12, including painful inflammation of my mouth tissues. Once starting these (and another natural-form B12 supplement), my symptoms went away after a month.

12/23/2019 11:00:00 pm

would buy again

by Marti -

I stay more alert taking this

10/7/2019 12:00:00 am

Excellent product

by Patricia -

Good combo of B12 without the cyan cobalamin.

2/20/2019 11:00:00 pm

Great for MTHFR gene mutation patients

by AshleySB -

Great for those who have an MTHFR gene mutation. I have seen great improvements from switching to this adenosyl/hydroxy blend last year, even from using a methylated version before.

11/13/2018 11:00:00 pm

No jitters

by Billye -

I have the MTHFR gene. This B12 is perfect for me.

3/18/2017 12:00:00 am


by Bob -


3/15/2017 12:00:00 am

Great B12 Supplement

by Ty -

This is an excellent Vitamin B12 supplement. Adenosylcobalamin is critically important and required for the methylation process. Adenosylcobalamin is also critically important for the health of the liver, brain, and nervous system. I like that this product comes in a small vegan capsule. It is also free of chemical additives such as magnesium stearate, citric acid, and ""natural flavors"" produced from monosodium glutamate that are found in most Vitamin B12 supplements.

3/14/2017 12:00:00 am

Great if you react to other B12's

by Ela -

This is high quality B12. My genetic testing indicates that this combination is best for me. It is the only hydroxy and adenosyl I have found that is free of ingredients I cannot tolerate. Simply the best.