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Pregnenolone tablets may be a useful nutritional supplement for individuals wishing to supplement their diet with pregnenolone for hormone support.
Pregnenolone 5 mg, provided by Douglas Laboratories® contains the highest purity pregnenolone and is produced under strict Good Manufacturing Practices (GMP) standards.
Pregnenolone is often referred to as the grandparent precursor to steroid hormones in mammals. Pregnenolone is synthesized from cholesterol in the mitochondria of adrenal glands. Pregnenolone is also made to a lesser extent in the brain, liver, skin, testes and ovaries. Once synthesized, pregnenolone is released from the mitochondria into the cytosol where it can be converted to DHEA (dehydroepiandrosterone) or to progesterone. DHEA serves as a precursor compound to the androgens and the estrogens through androstenedione as the intermediate compound.
Progesterone is the precursor to cortisol, aldosterone, androstenedione, estrogen, and testosterone. Pregnenolone may also be secreted directly into the blood where it circulates primarily as the sulfated form. Pregnenolone has many actions of its own not attributable to its conversion to progesterone or to DHEA. Recent studies show that pregnenolone is important for the function of brain, nervous tissue, liver, pancreas, reproductive tissues, pituitary and skin. Pregnenolone is found in higher concentrations in the central nervous system compared to the peripheral tissues which may reflect its importance in brain function. As with many hormones, pregnenolone production declines with age. It is estimated that pregnenolone production is about 60% less at age 75 than at age 35. Pregnenolone levels may also decline under various conditions of physiological stress, such as acute and chronic infections and trauma.
Please consult your physician before using this product.
As a dietary supplement, adults take ½ to 1 tablet daily, as directed by your healthcare professional only.
Allow tablet to dissolve in mouth and then swallow.
- Serving size: 1 Bisected Tablet
- Servings Per Container: 100
- Amount Per Serving:
- Pregnenolone 5 mg
Other Ingredients: Mannitol, cellulose, silica and vegetagle stearate.
This product contains NO yeast, wheat, gluten, soy protein, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring.
Not for use by individuals under the age of 18 years. Do not use if pregnant or nursing.
Consult a physician or licensed qualified health care professional before using this product if you have or have a family history of breat cancer, uterine cancer, ovarian cancer, prostate cancer, prostate enlargement, heart disease, low HDL cholesterol ("good cholesterol"), or if you are using any other dietary supplement, prescription drug, or over-the-counter drug. Do not exceed the recommended serving. Exceeding the recommended serving may cause serious adverse health effects.
Possible side effects include changes in liver function, acne, hair loss, hair growth on the face (in women), aggressiveness, irritability, and increased levels of estrogen.
Discontinue use and call a physician or licensed qualified health care professional immediately if you experience rapid heartbeat, dizziness, blurred vision, or other similar symptoms.
Keep out of reach of children.
For optimal storage conditions, store in a cool, dry place.